BCL-2 inhibition impairs mitochondrial function and targets oral tongue squamous cell carcinoma

PURPOSE: To understand the role of Bcl-2 overexpression in oral tongue squamous cell carcinoma (OTSCC) patients and investigate the efficacy of targeting Bcl-2 in OTSCC. METHODS: The expression level of Bcl-2 on normal tongue cells and OTSCC cells were measured by real-time PCR and western blotting....

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Detalles Bibliográficos
Autores principales: Xiong, Lei, Tang, Yi, Liu, Zhaoyang, Dai, Jing, Wang, Xiaozhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031576/
https://www.ncbi.nlm.nih.gov/pubmed/27722045
http://dx.doi.org/10.1186/s40064-016-3310-2

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