The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin

AGAP1 is an Arf1 GTPase activating protein that interacts with the vesicle-associated protein complexes adaptor protein 3 (AP-3) and Biogenesis of Lysosome Related Organelles Complex-1 (BLOC-1). Overexpression of AGAP1 in non-neuronal cells results in an accumulation of endosomal cargoes, which sugg...

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Detalles Bibliográficos
Autores principales: Arnold, Miranda, Cross, Rebecca, Singleton, Kaela S., Zlatic, Stephanie, Chapleau, Christopher, Mullin, Ariana P., Rolle, Isaiah, Moore, Carlene C., Theibert, Anne, Pozzo-Miller, Lucas, Faundez, Victor, Larimore, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031601/
https://www.ncbi.nlm.nih.gov/pubmed/27713690
http://dx.doi.org/10.3389/fncel.2016.00218

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