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Structural basis of synaptic vesicle assembly promoted by α-synuclein
α-synuclein (αS) is an intrinsically disordered protein whose fibrillar aggregates are the major constituents of Lewy bodies in Parkinson's disease. Although the specific function of αS is still unclear, a general consensus is forming that it has a key role in regulating the process of neurotra...
Autores principales: | Fusco, Giuliana, Pape, Tillmann, Stephens, Amberley D., Mahou, Pierre, Costa, Ana Rita, Kaminski, Clemens F., Kaminski Schierle, Gabriele S., Vendruscolo, Michele, Veglia, Gianluigi, Dobson, Christopher M., De Simone, Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031799/ https://www.ncbi.nlm.nih.gov/pubmed/27640673 http://dx.doi.org/10.1038/ncomms12563 |
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