Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia()

Preclinical studies have suggested that the pancreatic tumor microenvironment both inhibits and promotes tumor development and growth. Here we establish the role of stromal fibroblasts during acinar-to-ductal metaplasia (ADM), an initiating event in pancreatic cancer formation. The transcription fac...

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Detalles Bibliográficos
Autores principales: Pitarresi, Jason R., Liu, Xin, Sharma, Sudarshana M., Cuitiño, Maria C., Kladney, Raleigh D., Mace, Thomas A., Donohue, Sydney, Nayak, Sunayana G., Qu, Chunjing, Lee, James, Woelke, Sarah A., Trela, Stefan, LaPak, Kyle, Yu, Lianbo, McElroy, Joseph, Rosol, Thomas J., Shakya, Reena, Ludwig, Thomas, Lesinski, Gregory B., Fernandez, Soledad A., Konieczny, Stephen F., Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031867/
https://www.ncbi.nlm.nih.gov/pubmed/27659014
http://dx.doi.org/10.1016/j.neo.2016.07.006

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