Clinical Genotyping of Non–Small Cell Lung Cancers Using Targeted Next-Generation Sequencing: Utility of Identifying Rare and Co-mutations in Oncogenic Driver Genes()

Detection of somatic mutations in non–small cell lung cancers (NSCLCs), especially adenocarcinomas, is important for directing patient care when targeted therapy is available. Here, we present our experience with genotyping NSCLC using the Ion Torrent Personal Genome Machine (PGM) and the AmpliSeq C...

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Detalles Bibliográficos
Autores principales: Tafe, Laura J., Pierce, Kirsten J., Peterson, Jason D., de Abreu, Francine, Memoli, Vincent A., Black, Candice C., Pettus, Jason R., Marotti, Jonathan D., Gutmann, Edward J., Liu, Xiaoying, Shirai, Keisuke, Dragnev, Konstantin H., Amos, Christopher I., Tsongalis, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031899/
https://www.ncbi.nlm.nih.gov/pubmed/27659017
http://dx.doi.org/10.1016/j.neo.2016.07.010

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