Hypoxia-Inducible Factor 2α Mutation-Related Paragangliomas Classify as Discrete Pseudohypoxic Subcluster()()

Recently, activating mutations of the hypoxia-inducible factor 2α gene (HIF2A/EPAS1) have been recognized to predispose to multiple paragangliomas (PGLs) and duodenal somatostatinomas associated with polycythemia, and ocular abnormalities. Previously, mutations in the SDHA/B/C/D, SDHAF2, VHL, FH, PH...

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Detalles Bibliográficos
Autores principales: Fliedner, Stephanie M.J., Shankavaram, Uma, Marzouca, Geena, Elkahloun, Abdel, Jochmanova, Ivana, Daerr, Roland, Linehan, W. Marston, Timmers, Henri, Tischler, Arthur S., Papaspyrou, Konstantinos, Brieger, Jürgen, de Krijger, Ronald, Breza, Jan, Eisenhofer, Graeme, Zhuang, Zhengping, Lehnert, Hendrik, Pacak, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031903/
https://www.ncbi.nlm.nih.gov/pubmed/27659016
http://dx.doi.org/10.1016/j.neo.2016.07.008

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