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Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes
This paper considers novel Bayesian non-parametric methods for stochastic epidemic models. Many standard modeling and data analysis methods use underlying assumptions (e.g. concerning the rate at which new cases of disease will occur) which are rarely challenged or tested in practice. To relax these...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031942/ https://www.ncbi.nlm.nih.gov/pubmed/26993062 http://dx.doi.org/10.1093/biostatistics/kxw011 |
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author | Xu, Xiaoguang Kypraios, Theodore O'Neill, Philip D |
author_facet | Xu, Xiaoguang Kypraios, Theodore O'Neill, Philip D |
author_sort | Xu, Xiaoguang |
collection | PubMed |
description | This paper considers novel Bayesian non-parametric methods for stochastic epidemic models. Many standard modeling and data analysis methods use underlying assumptions (e.g. concerning the rate at which new cases of disease will occur) which are rarely challenged or tested in practice. To relax these assumptions, we develop a Bayesian non-parametric approach using Gaussian Processes, specifically to estimate the infection process. The methods are illustrated with both simulated and real data sets, the former illustrating that the methods can recover the true infection process quite well in practice, and the latter illustrating that the methods can be successfully applied in different settings. |
format | Online Article Text |
id | pubmed-5031942 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-50319422016-09-23 Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes Xu, Xiaoguang Kypraios, Theodore O'Neill, Philip D Biostatistics Articles This paper considers novel Bayesian non-parametric methods for stochastic epidemic models. Many standard modeling and data analysis methods use underlying assumptions (e.g. concerning the rate at which new cases of disease will occur) which are rarely challenged or tested in practice. To relax these assumptions, we develop a Bayesian non-parametric approach using Gaussian Processes, specifically to estimate the infection process. The methods are illustrated with both simulated and real data sets, the former illustrating that the methods can recover the true infection process quite well in practice, and the latter illustrating that the methods can be successfully applied in different settings. Oxford University Press 2016-10 2016-03-18 /pmc/articles/PMC5031942/ /pubmed/26993062 http://dx.doi.org/10.1093/biostatistics/kxw011 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Xu, Xiaoguang Kypraios, Theodore O'Neill, Philip D Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes |
title | Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes |
title_full | Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes |
title_fullStr | Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes |
title_full_unstemmed | Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes |
title_short | Bayesian non-parametric inference for stochastic epidemic models using Gaussian Processes |
title_sort | bayesian non-parametric inference for stochastic epidemic models using gaussian processes |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031942/ https://www.ncbi.nlm.nih.gov/pubmed/26993062 http://dx.doi.org/10.1093/biostatistics/kxw011 |
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