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Accounting for selection and correlation in the analysis of two-stage genome-wide association studies

The problem of selection bias has long been recognized in the analysis of two-stage trials, where promising candidates are selected in stage 1 for confirmatory analysis in stage 2. To efficiently correct for bias, uniformly minimum variance conditionally unbiased estimators (UMVCUEs) have been propo...

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Detalles Bibliográficos
Autores principales:	Robertson, David S., Prevost, A. Toby, Bowden, Jack
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031943/ https://www.ncbi.nlm.nih.gov/pubmed/26993061 http://dx.doi.org/10.1093/biostatistics/kxw012

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