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High throughput sequencing analysis of RNA libraries reveals the influences of initial library and PCR methods on SELEX efficiency
The systemic evolution of ligands by exponential enrichment (SELEX) technique is a powerful and effective aptamer-selection procedure. However, modifications to the process can dramatically improve selection efficiency and aptamer performance. For example, droplet digital PCR (ddPCR) has been recent...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031971/ https://www.ncbi.nlm.nih.gov/pubmed/27652575 http://dx.doi.org/10.1038/srep33697 |