Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer

Metastatic breast cancers are aggressive tumors associated with high levels of epithelial-mesenchymal transition (EMT) markers, activation of IL6/JAK2/STAT3 and PI3K/AKT pathways for cell growth, mobility, invasion, metastasis, and CSC status. We identified a new molecular and functional network pre...

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Detalles Bibliográficos
Autores principales: Kim, Min Soo, Jeong, Joon, Seo, Jeongbeob, Kim, Hae-Suk, Kim, Seong-Jin, Jin, Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032000/
https://www.ncbi.nlm.nih.gov/pubmed/27654855
http://dx.doi.org/10.1038/srep33899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032000/
https://www.ncbi.nlm.nih.gov/pubmed/27654855
http://dx.doi.org/10.1038/srep33899

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