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Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source

AIM OF THE STUDY: The (57)Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated an...

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Autores principales: Toossi, Mohammad Taghi Bahreyni, Ghorbani, Mahdi, Rostami, Atefeh, Khosroabadi, Mohsen, Khademi, Sara, Knaup, Courtney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032162/
https://www.ncbi.nlm.nih.gov/pubmed/27688731
http://dx.doi.org/10.5114/wo.2016.61854
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author Toossi, Mohammad Taghi Bahreyni
Ghorbani, Mahdi
Rostami, Atefeh
Khosroabadi, Mohsen
Khademi, Sara
Knaup, Courtney
author_facet Toossi, Mohammad Taghi Bahreyni
Ghorbani, Mahdi
Rostami, Atefeh
Khosroabadi, Mohsen
Khademi, Sara
Knaup, Courtney
author_sort Toossi, Mohammad Taghi Bahreyni
collection PubMed
description AIM OF THE STUDY: The (57)Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical (57)Co source. MATERIAL AND METHODS: A hypothetical (57)Co source was simulated in MCNPX, consisting of an active cylinder with 3.5 mm length and 0.6 mm radius encapsulated in a stainless steel capsule. Three photon energies were utilized (136 keV [10.68%], 122 keV [85.60%], 14 keV [9.16%]) for the (57)Co source. Air kerma strength, dose rate constant, radial dose function, anisotropy function, and isodose curves for the source were calculated and compared to the corresponding data for a (192)Ir source. RESULTS: The results are presented as tables and figures. Air kerma strength per 1 mCi activity for the (57)Co source was 0.46 cGyh(–1) cm 2 mCi(–1). The dose rate constant for the (57)Co source was determined to be 1.215 cGyh(–1)U(–1). The radial dose function for the (57)Co source has an increasing trend due to multiple scattering of low energy photons. The anisotropy function for the (57)Co source at various distances from the source is more isotropic than the (192)Ir source. CONCLUSIONS: The (57)Co source has advantages over (192)Ir due to its lower energy photons, longer half-life, higher dose rate constant and more isotropic anisotropic function. However, the (192)Ir source has a higher initial air kerma strength and more uniform radial dose function. These properties make (57)Co a suitable source for use in brachytherapy applications.
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spelling pubmed-50321622016-09-29 Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source Toossi, Mohammad Taghi Bahreyni Ghorbani, Mahdi Rostami, Atefeh Khosroabadi, Mohsen Khademi, Sara Knaup, Courtney Contemp Oncol (Pozn) Original Paper AIM OF THE STUDY: The (57)Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical (57)Co source. MATERIAL AND METHODS: A hypothetical (57)Co source was simulated in MCNPX, consisting of an active cylinder with 3.5 mm length and 0.6 mm radius encapsulated in a stainless steel capsule. Three photon energies were utilized (136 keV [10.68%], 122 keV [85.60%], 14 keV [9.16%]) for the (57)Co source. Air kerma strength, dose rate constant, radial dose function, anisotropy function, and isodose curves for the source were calculated and compared to the corresponding data for a (192)Ir source. RESULTS: The results are presented as tables and figures. Air kerma strength per 1 mCi activity for the (57)Co source was 0.46 cGyh(–1) cm 2 mCi(–1). The dose rate constant for the (57)Co source was determined to be 1.215 cGyh(–1)U(–1). The radial dose function for the (57)Co source has an increasing trend due to multiple scattering of low energy photons. The anisotropy function for the (57)Co source at various distances from the source is more isotropic than the (192)Ir source. CONCLUSIONS: The (57)Co source has advantages over (192)Ir due to its lower energy photons, longer half-life, higher dose rate constant and more isotropic anisotropic function. However, the (192)Ir source has a higher initial air kerma strength and more uniform radial dose function. These properties make (57)Co a suitable source for use in brachytherapy applications. Termedia Publishing House 2016-09-05 2016 /pmc/articles/PMC5032162/ /pubmed/27688731 http://dx.doi.org/10.5114/wo.2016.61854 Text en Copyright: © 2016 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Toossi, Mohammad Taghi Bahreyni
Ghorbani, Mahdi
Rostami, Atefeh
Khosroabadi, Mohsen
Khademi, Sara
Knaup, Courtney
Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source
title Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source
title_full Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source
title_fullStr Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source
title_full_unstemmed Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source
title_short Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source
title_sort comparison of the hypothetical (57)co brachytherapy source with the (192)ir source
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032162/
https://www.ncbi.nlm.nih.gov/pubmed/27688731
http://dx.doi.org/10.5114/wo.2016.61854
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