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Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source
AIM OF THE STUDY: The (57)Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032162/ https://www.ncbi.nlm.nih.gov/pubmed/27688731 http://dx.doi.org/10.5114/wo.2016.61854 |
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author | Toossi, Mohammad Taghi Bahreyni Ghorbani, Mahdi Rostami, Atefeh Khosroabadi, Mohsen Khademi, Sara Knaup, Courtney |
author_facet | Toossi, Mohammad Taghi Bahreyni Ghorbani, Mahdi Rostami, Atefeh Khosroabadi, Mohsen Khademi, Sara Knaup, Courtney |
author_sort | Toossi, Mohammad Taghi Bahreyni |
collection | PubMed |
description | AIM OF THE STUDY: The (57)Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical (57)Co source. MATERIAL AND METHODS: A hypothetical (57)Co source was simulated in MCNPX, consisting of an active cylinder with 3.5 mm length and 0.6 mm radius encapsulated in a stainless steel capsule. Three photon energies were utilized (136 keV [10.68%], 122 keV [85.60%], 14 keV [9.16%]) for the (57)Co source. Air kerma strength, dose rate constant, radial dose function, anisotropy function, and isodose curves for the source were calculated and compared to the corresponding data for a (192)Ir source. RESULTS: The results are presented as tables and figures. Air kerma strength per 1 mCi activity for the (57)Co source was 0.46 cGyh(–1) cm 2 mCi(–1). The dose rate constant for the (57)Co source was determined to be 1.215 cGyh(–1)U(–1). The radial dose function for the (57)Co source has an increasing trend due to multiple scattering of low energy photons. The anisotropy function for the (57)Co source at various distances from the source is more isotropic than the (192)Ir source. CONCLUSIONS: The (57)Co source has advantages over (192)Ir due to its lower energy photons, longer half-life, higher dose rate constant and more isotropic anisotropic function. However, the (192)Ir source has a higher initial air kerma strength and more uniform radial dose function. These properties make (57)Co a suitable source for use in brachytherapy applications. |
format | Online Article Text |
id | pubmed-5032162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-50321622016-09-29 Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source Toossi, Mohammad Taghi Bahreyni Ghorbani, Mahdi Rostami, Atefeh Khosroabadi, Mohsen Khademi, Sara Knaup, Courtney Contemp Oncol (Pozn) Original Paper AIM OF THE STUDY: The (57)Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical (57)Co source. MATERIAL AND METHODS: A hypothetical (57)Co source was simulated in MCNPX, consisting of an active cylinder with 3.5 mm length and 0.6 mm radius encapsulated in a stainless steel capsule. Three photon energies were utilized (136 keV [10.68%], 122 keV [85.60%], 14 keV [9.16%]) for the (57)Co source. Air kerma strength, dose rate constant, radial dose function, anisotropy function, and isodose curves for the source were calculated and compared to the corresponding data for a (192)Ir source. RESULTS: The results are presented as tables and figures. Air kerma strength per 1 mCi activity for the (57)Co source was 0.46 cGyh(–1) cm 2 mCi(–1). The dose rate constant for the (57)Co source was determined to be 1.215 cGyh(–1)U(–1). The radial dose function for the (57)Co source has an increasing trend due to multiple scattering of low energy photons. The anisotropy function for the (57)Co source at various distances from the source is more isotropic than the (192)Ir source. CONCLUSIONS: The (57)Co source has advantages over (192)Ir due to its lower energy photons, longer half-life, higher dose rate constant and more isotropic anisotropic function. However, the (192)Ir source has a higher initial air kerma strength and more uniform radial dose function. These properties make (57)Co a suitable source for use in brachytherapy applications. Termedia Publishing House 2016-09-05 2016 /pmc/articles/PMC5032162/ /pubmed/27688731 http://dx.doi.org/10.5114/wo.2016.61854 Text en Copyright: © 2016 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Original Paper Toossi, Mohammad Taghi Bahreyni Ghorbani, Mahdi Rostami, Atefeh Khosroabadi, Mohsen Khademi, Sara Knaup, Courtney Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source |
title | Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source |
title_full | Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source |
title_fullStr | Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source |
title_full_unstemmed | Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source |
title_short | Comparison of the hypothetical (57)Co brachytherapy source with the (192)Ir source |
title_sort | comparison of the hypothetical (57)co brachytherapy source with the (192)ir source |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032162/ https://www.ncbi.nlm.nih.gov/pubmed/27688731 http://dx.doi.org/10.5114/wo.2016.61854 |
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