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24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure

In the central nervous system, 24(S)-hydroxycholesterol (24(S)-HC) is an oxysterol synthesized from cholesterol by cholesterol 24-hydroxylase (CYP46A1) encoded by the cyp46a1 gene. In the present study using a rat ex vivo glaucoma model, we found that retinal 24(S)-HC synthesis is facilitated by pre...

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Detalles Bibliográficos
Autores principales:	Ishikawa, Makoto, Yoshitomi, Takeshi, Zorumski, Charles F., Izumi, Yukitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032171/ https://www.ncbi.nlm.nih.gov/pubmed/27653972 http://dx.doi.org/10.1038/srep33886

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