Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β

The cell surface proteoglycan syndecan 1 (SDC1) is overexpressed in the malignant breast stromal fibroblasts, creating a favorable milieu for tumor cell growth. In the present study, we found that ionizing radiation, a well-established treatment in human breast cancer, provokes premature senescence...

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Detalles Bibliográficos
Autores principales: Liakou, Eleni, Mavrogonatou, Eleni, Pratsinis, Harris, Rizou, Sophia, Evangelou, Konstantinos, Panagiotou, Petros N., Karamanos, Nikos K., Gorgoulis, Vassilis G., Kletsas, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032688/
https://www.ncbi.nlm.nih.gov/pubmed/27434331
http://dx.doi.org/10.18632/aging.100989

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