Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes

Aging and exposure to stress would determine the chondrocyte phenotype in osteoarthritis (OA). In particular, chronic inflammation may contribute to stress-induced senescence of chondrocytes and cartilage degeneration during OA progression. Recent studies have shown that adipose-derived mesenchymal...

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Detalles Bibliográficos
Autores principales: Platas, Julia, Guillén, Maria Isabel, del Caz, Maria Dolores Pérez, Gomar, Francisco, Castejón, Miguel Angel, Mirabet, Vicente, Alcaraz, Maria José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032691/
https://www.ncbi.nlm.nih.gov/pubmed/27490266
http://dx.doi.org/10.18632/aging.101007

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