Cargando…

Quantitative proteomics of rat livers shows that unrestricted feeding is stressful for proteostasis with implications on life span

Studies in young mammals on the molecular effects of food restriction leading to prolong adult life are scares. Here, we used high-throughput quantitative proteomic analysis of whole rat livers to address the molecular basis for growth arrest and the apparent life-prolonging phenotype of the food re...

Descripción completa

Detalles Bibliográficos
Autores principales: Gat-Yablonski, Galia, Finka, Andrija, Pinto, Galit, Quadroni, Manfredo, Shtaif, Biana, Goloubinoff, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032693/
https://www.ncbi.nlm.nih.gov/pubmed/27508340
http://dx.doi.org/10.18632/aging.101009