Modeling the Chronic Loss of Optic Nerve Axons and the Effects on the Retinal Nerve Fiber Layer Structure in Primary Disorder of Myelin

PURPOSE: We determined whether the chronic lack of optic nerve myelination and subsequent axon loss is associated with optical coherence tomography (OCT) changes in the retinal nerve fiber layer (RNFL), and whether this models what occurs in multiple sclerosis (MS) and confers its use as a surrogate...

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Detalles Bibliográficos
Autores principales: Teixeira, Leandro B. C., Ver Hoeve, James N., Mayer, Joshua A., Dubielzig, Richard R., Smith, Chelsey M., Radcliff, Abigail B., Duncan, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032912/
https://www.ncbi.nlm.nih.gov/pubmed/27654412
http://dx.doi.org/10.1167/iovs.16-19871

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