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Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)

HPV infection is an important public health problem in developing countries. We investigated HPV genotypes in the Uyghur female population of Karasay Township, Hotan region. A population‐based cervical cancer screening was conducted for 4,500 women in Karasay Township, Xinjiang Hotan, China. A total...

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Autores principales: Mijit, Fatima, Ablimit, Tangnur, Abduxkur, Guzalnur, Abliz, Guzalnur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033003/
https://www.ncbi.nlm.nih.gov/pubmed/26081269
http://dx.doi.org/10.1002/jmv.24240
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author Mijit, Fatima
Ablimit, Tangnur
Abduxkur, Guzalnur
Abliz, Guzalnur
author_facet Mijit, Fatima
Ablimit, Tangnur
Abduxkur, Guzalnur
Abliz, Guzalnur
author_sort Mijit, Fatima
collection PubMed
description HPV infection is an important public health problem in developing countries. We investigated HPV genotypes in the Uyghur female population of Karasay Township, Hotan region. A population‐based cervical cancer screening was conducted for 4,500 women in Karasay Township, Xinjiang Hotan, China. A total of 900 women were selected by systematic sampling with a 5:1 proportion (ages 20–69). The subjects completed a questionnaire and consented to HPV typing and Pap smear examination. Colposcopic biopsies were performed for patients with cytological abnormalities (≥ASCUS). A total of 117 of the 900 women (13%) assessed were infected with HPV. The most common subtype was HPV‐16, and other common high‐risk types included HPV‐58 and HPV‐39. A total of 40 women (4.44%) were identified with abnormal cytology (≥ASCUS) by Pap smear. A significant link was found between HPV prevalence and cytological diagnosis. The HPV infection rates for the patients with cervical inflammation, CIN, and cancer were 18.18%, 64.71%, and 100%, respectively. Significant differences in HPV infection rates were found among the patients with the three groups of pathological results. In Karasay, the HPV infection rate in Uyghur women is lower than previously reported; however, the proportion infected with HR‐HPV is higher. HPV‐16, HPV‐58, and HPV‐39 are the most prevalent genotypes. J. Med. Virol. 87:1960–1965, 2015. © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc.
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spelling pubmed-50330032016-10-03 Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) Mijit, Fatima Ablimit, Tangnur Abduxkur, Guzalnur Abliz, Guzalnur J Med Virol Research Articles HPV infection is an important public health problem in developing countries. We investigated HPV genotypes in the Uyghur female population of Karasay Township, Hotan region. A population‐based cervical cancer screening was conducted for 4,500 women in Karasay Township, Xinjiang Hotan, China. A total of 900 women were selected by systematic sampling with a 5:1 proportion (ages 20–69). The subjects completed a questionnaire and consented to HPV typing and Pap smear examination. Colposcopic biopsies were performed for patients with cytological abnormalities (≥ASCUS). A total of 117 of the 900 women (13%) assessed were infected with HPV. The most common subtype was HPV‐16, and other common high‐risk types included HPV‐58 and HPV‐39. A total of 40 women (4.44%) were identified with abnormal cytology (≥ASCUS) by Pap smear. A significant link was found between HPV prevalence and cytological diagnosis. The HPV infection rates for the patients with cervical inflammation, CIN, and cancer were 18.18%, 64.71%, and 100%, respectively. Significant differences in HPV infection rates were found among the patients with the three groups of pathological results. In Karasay, the HPV infection rate in Uyghur women is lower than previously reported; however, the proportion infected with HR‐HPV is higher. HPV‐16, HPV‐58, and HPV‐39 are the most prevalent genotypes. J. Med. Virol. 87:1960–1965, 2015. © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc. John Wiley and Sons Inc. 2015-11 2015-06-16 /pmc/articles/PMC5033003/ /pubmed/26081269 http://dx.doi.org/10.1002/jmv.24240 Text en © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
Mijit, Fatima
Ablimit, Tangnur
Abduxkur, Guzalnur
Abliz, Guzalnur
Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)
title Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)
title_full Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)
title_fullStr Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)
title_full_unstemmed Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)
title_short Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)
title_sort distribution of human papillomavirus (hpv) genotypes detected by routine pap smear in uyghur‐muslim women from karasay township hotan (xinjiang, china)
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033003/
https://www.ncbi.nlm.nih.gov/pubmed/26081269
http://dx.doi.org/10.1002/jmv.24240
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