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Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China)
HPV infection is an important public health problem in developing countries. We investigated HPV genotypes in the Uyghur female population of Karasay Township, Hotan region. A population‐based cervical cancer screening was conducted for 4,500 women in Karasay Township, Xinjiang Hotan, China. A total...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033003/ https://www.ncbi.nlm.nih.gov/pubmed/26081269 http://dx.doi.org/10.1002/jmv.24240 |
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author | Mijit, Fatima Ablimit, Tangnur Abduxkur, Guzalnur Abliz, Guzalnur |
author_facet | Mijit, Fatima Ablimit, Tangnur Abduxkur, Guzalnur Abliz, Guzalnur |
author_sort | Mijit, Fatima |
collection | PubMed |
description | HPV infection is an important public health problem in developing countries. We investigated HPV genotypes in the Uyghur female population of Karasay Township, Hotan region. A population‐based cervical cancer screening was conducted for 4,500 women in Karasay Township, Xinjiang Hotan, China. A total of 900 women were selected by systematic sampling with a 5:1 proportion (ages 20–69). The subjects completed a questionnaire and consented to HPV typing and Pap smear examination. Colposcopic biopsies were performed for patients with cytological abnormalities (≥ASCUS). A total of 117 of the 900 women (13%) assessed were infected with HPV. The most common subtype was HPV‐16, and other common high‐risk types included HPV‐58 and HPV‐39. A total of 40 women (4.44%) were identified with abnormal cytology (≥ASCUS) by Pap smear. A significant link was found between HPV prevalence and cytological diagnosis. The HPV infection rates for the patients with cervical inflammation, CIN, and cancer were 18.18%, 64.71%, and 100%, respectively. Significant differences in HPV infection rates were found among the patients with the three groups of pathological results. In Karasay, the HPV infection rate in Uyghur women is lower than previously reported; however, the proportion infected with HR‐HPV is higher. HPV‐16, HPV‐58, and HPV‐39 are the most prevalent genotypes. J. Med. Virol. 87:1960–1965, 2015. © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc. |
format | Online Article Text |
id | pubmed-5033003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-50330032016-10-03 Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) Mijit, Fatima Ablimit, Tangnur Abduxkur, Guzalnur Abliz, Guzalnur J Med Virol Research Articles HPV infection is an important public health problem in developing countries. We investigated HPV genotypes in the Uyghur female population of Karasay Township, Hotan region. A population‐based cervical cancer screening was conducted for 4,500 women in Karasay Township, Xinjiang Hotan, China. A total of 900 women were selected by systematic sampling with a 5:1 proportion (ages 20–69). The subjects completed a questionnaire and consented to HPV typing and Pap smear examination. Colposcopic biopsies were performed for patients with cytological abnormalities (≥ASCUS). A total of 117 of the 900 women (13%) assessed were infected with HPV. The most common subtype was HPV‐16, and other common high‐risk types included HPV‐58 and HPV‐39. A total of 40 women (4.44%) were identified with abnormal cytology (≥ASCUS) by Pap smear. A significant link was found between HPV prevalence and cytological diagnosis. The HPV infection rates for the patients with cervical inflammation, CIN, and cancer were 18.18%, 64.71%, and 100%, respectively. Significant differences in HPV infection rates were found among the patients with the three groups of pathological results. In Karasay, the HPV infection rate in Uyghur women is lower than previously reported; however, the proportion infected with HR‐HPV is higher. HPV‐16, HPV‐58, and HPV‐39 are the most prevalent genotypes. J. Med. Virol. 87:1960–1965, 2015. © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc. John Wiley and Sons Inc. 2015-11 2015-06-16 /pmc/articles/PMC5033003/ /pubmed/26081269 http://dx.doi.org/10.1002/jmv.24240 Text en © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Research Articles Mijit, Fatima Ablimit, Tangnur Abduxkur, Guzalnur Abliz, Guzalnur Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) |
title | Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) |
title_full | Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) |
title_fullStr | Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) |
title_full_unstemmed | Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) |
title_short | Distribution of human papillomavirus (HPV) genotypes detected by routine pap smear in uyghur‐muslim women from Karasay Township Hotan (Xinjiang, China) |
title_sort | distribution of human papillomavirus (hpv) genotypes detected by routine pap smear in uyghur‐muslim women from karasay township hotan (xinjiang, china) |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033003/ https://www.ncbi.nlm.nih.gov/pubmed/26081269 http://dx.doi.org/10.1002/jmv.24240 |
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