Densely Packed Microgoblet Laser Pairs for Cross‐Referenced Biomolecular Detection

Microgoblet laser pairs are presented for cross‐referenced on‐chip biomolecular sensing. Parallel readout of the micro­lasers facilitates effective mutual filtering of highly localized refractive index and temperature fluctuations in the analyte. Cross‐referenced detection of two different types of...

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Detalles Bibliográficos
Autores principales: Bog, Uwe, Brinkmann, Falko, Wondimu, Sentayehu Fetene, Wienhold, Tobias, Kraemmer, Sarah, Koos, Christian, Kalt, Heinz, Hirtz, Michael, Fuchs, Harald, Koeber, Sebastian, Mappes, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033028/
https://www.ncbi.nlm.nih.gov/pubmed/27708994
http://dx.doi.org/10.1002/advs.201500066
Descripción
Sumario:Microgoblet laser pairs are presented for cross‐referenced on‐chip biomolecular sensing. Parallel readout of the micro­lasers facilitates effective mutual filtering of highly localized refractive index and temperature fluctuations in the analyte. Cross‐referenced detection of two different types of proteins and complete chemical transducer reconfiguration is demonstrated. Selective surface functionalization of the individual lasers with high spatial accuracy is achieved by aligned microcontact stamping. [Image: see text]

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