Bromodomain and Extra Terminal (BET) Inhibitor Suppresses Macrophage-Driven Steroid-Resistant Exacerbations of Airway Hyper-Responsiveness and Inflammation

BACKGROUND: Exacerbations of asthma are linked to significant decline in lung function and are often poorly controlled by corticosteroid treatment. Clinical investigations indicate that viral and bacterial infections play crucial roles in the onset of steroid-resistant inflammation and airways hyper...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Hiep, Maltby, Steven, Eyers, Fiona, Foster, Paul S., Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033241/
https://www.ncbi.nlm.nih.gov/pubmed/27657907
http://dx.doi.org/10.1371/journal.pone.0163392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033241/
https://www.ncbi.nlm.nih.gov/pubmed/27657907
http://dx.doi.org/10.1371/journal.pone.0163392

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