Aberrant Methylation of MGMT Promoter in HNSCC: A Meta-Analysis

BACKGROUND: O6-methylguanine-DNA methyl-transferase (MGMT) gene, a DNA repair gene, plays a critical role in the repair of alkylated DNA adducts that form following exposure to genotoxic agents. MGMT is generally expressed in various tumors, and its function is frequently lost because of hypermethyl...

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Detalles Bibliográficos
Autores principales: Cai, Fucheng, Xiao, Xiyue, Niu, Xun, Shi, Hao, Zhong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033341/
https://www.ncbi.nlm.nih.gov/pubmed/27657735
http://dx.doi.org/10.1371/journal.pone.0163534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033341/
https://www.ncbi.nlm.nih.gov/pubmed/27657735
http://dx.doi.org/10.1371/journal.pone.0163534

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