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Aberrant Methylation of MGMT Promoter in HNSCC: A Meta-Analysis
BACKGROUND: O6-methylguanine-DNA methyl-transferase (MGMT) gene, a DNA repair gene, plays a critical role in the repair of alkylated DNA adducts that form following exposure to genotoxic agents. MGMT is generally expressed in various tumors, and its function is frequently lost because of hypermethyl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033341/ https://www.ncbi.nlm.nih.gov/pubmed/27657735 http://dx.doi.org/10.1371/journal.pone.0163534 |