Vimentin, a Novel NF-κB Regulator, Is Required for Meningitic Escherichia coli K1-Induced Pathogen Invasion and PMN Transmigration across the Blood-Brain Barrier

BACKGROUND: NF-κB activation, pathogen invasion, polymorphonuclear leukocytes (PMN) transmigration (PMNT) across the blood-brain barrier (BBB) are the pathogenic triad hallmark features of bacterial meningitis, but the mechanisms underlying these events remain largely unknown. Vimentin, which is a n...

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Detalles Bibliográficos
Autores principales: Huang, Sheng-He, Chi, Feng, Peng, Liang, Bo, Tao, Zhang, Bao, Liu, Li-Qun, Wu, Xuedong, Mor-Vaknin, Nirit, Markovitz, David M., Cao, Hong, Zhou, Yan-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033352/
https://www.ncbi.nlm.nih.gov/pubmed/27657497
http://dx.doi.org/10.1371/journal.pone.0162641

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