Cargando…

Immersed Boundary Models for Quantifying Flow-Induced Mechanical Stimuli on Stem Cells Seeded on 3D Scaffolds in Perfusion Bioreactors

Perfusion bioreactors regulate flow conditions in order to provide cells with oxygen, nutrients and flow-associated mechanical stimuli. Locally, these flow conditions can vary depending on the scaffold geometry, cellular confluency and amount of extra cellular matrix deposition. In this study, a nov...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guyot, Yann, Smeets, Bart, Odenthal, Tim, Subramani, Ramesh, Luyten, Frank P., Ramon, Herman, Papantoniou, Ioannis, Geris, Liesbet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033382/ https://www.ncbi.nlm.nih.gov/pubmed/27658116 http://dx.doi.org/10.1371/journal.pcbi.1005108

Ejemplares similares

Computational Modeling of Human Mesenchymal Stromal Cell Proliferation and Extra-Cellular Matrix Production in 3D Porous Scaffolds in a Perfusion Bioreactor: The Effect of Growth Factors
por: Mehrian, Mohammad, et al.
Publicado: (2020)

Human Platelet Lysate Improves Bone Forming Potential of Human Progenitor Cells Expanded in Microcarrier‐Based Dynamic Culture
por: Gupta, Priyanka, et al.
Publicado: (2019)

Stirred culture of cartilaginous microtissues promotes chondrogenic hypertrophy through exposure to intermittent shear stress
por: Loverdou, Niki, et al.
Publicado: (2022)

Developmentally Engineered Callus Organoid Bioassemblies Exhibit Predictive In Vivo Long Bone Healing
por: Nilsson Hall, Gabriella, et al.
Publicado: (2019)

Bioreactor-Based Online Recovery of Human Progenitor Cells with Uncompromised Regenerative Potential: A Bone Tissue Engineering Perspective
por: Sonnaert, Maarten, et al.
Publicado: (2015)

Experimental measurements and CFD modelling of hydroxyapatite scaffolds in perfusion bioreactors for bone regeneration
por: d’Adamo, Alessandro, et al.
Publicado: (2023)

Multifactorial Optimization of Contrast-Enhanced Nanofocus Computed Tomography for Quantitative Analysis of Neo-Tissue Formation in Tissue Engineering Constructs
por: Sonnaert, Maarten, et al.
Publicado: (2015)

Uncoupling of in-vitro identity of embryonic limb derived skeletal progenitors and their in-vivo bone forming potential
por: Verbeeck, Louca, et al.
Publicado: (2019)

In silico regenerative medicine: how computational tools allow regulatory and financial challenges to be addressed in a volatile market
por: Geris, L., et al.
Publicado: (2016)

Mechanical Regulation of Limb Bud Formation
por: Sermeus, Yvenn, et al.
Publicado: (2022)

Biochemical and Molecular Characterization of Musa sp. Cultured in Temporary Immersion Bioreactor
por: Sambolín Pérez, Christopher A., et al.
Publicado: (2023)

Immersed Boundary Simulations of Active Fluid Droplets
por: Whitfield, Carl A., et al.
Publicado: (2016)

Turning Nature’s own processes into design strategies for living bone implant biomanufacturing: a decade of Developmental Engineering
por: Papantoniou, Ioannis, et al.
Publicado: (2021)

In Vitro Hydrolytic Degradation of Polyester-Based Scaffolds under Static and Dynamic Conditions in a Customized Perfusion Bioreactor
por: Alamán-Díez, Pilar, et al.
Publicado: (2022)

Relating the Chondrocyte Gene Network to Growth Plate Morphology: From Genes to Phenotype
por: Kerkhofs, Johan, et al.
Publicado: (2012)

Single‐cell characterization and metabolic profiling of in vitro cultured human skeletal progenitors with enhanced in vivo bone forming capacity
por: Bolander, Johanna, et al.
Publicado: (2019)

The role of perfusion bioreactors in bone tissue engineering
por: Gaspar, Diana Alves, et al.
Publicado: (2012)

Evaluation of single-use bioreactors for perfusion processes
por: Polès-Lahille, Aurore, et al.
Publicado: (2013)

Computational Modeling in Tissue Engineering
por: Geris, Liesbet
Publicado: (2013)

A Qualitative Model of the Differentiation Network in Chondrocyte Maturation: A Holistic View of Chondrocyte Hypertrophy
por: Kerkhofs, Johan, et al.
Publicado: (2016)

Production of transgenic strawberries by temporary immersion bioreactor system and verification by TAIL-PCR
por: Hanhineva, Kati J, et al.
Publicado: (2007)

A Pattern-Based Approach for Detecting Pneumatic Failures on Temporary Immersion Bioreactors †
por: Loyola-González, Octavio, et al.
Publicado: (2019)

Changes in scaffold porosity during bone tissue engineering in perfusion bioreactors considerably affect cellular mechanical stimulation for mineralization
por: Zhao, Feihu, et al.
Publicado: (2020)

An optimized 3D-printed perfusion bioreactor for homogeneous cell seeding in bone substitute scaffolds for future chairside applications
por: Engel, Nadja, et al.
Publicado: (2021)

A high-efficiency discretized immersed boundary method for moving boundaries in incompressible flows
por: Xu, Dong, et al.
Publicado: (2023)

Engineering Tendon: Scaffolds, Bioreactors, and Models of Regeneration
por: Youngstrom, Daniel W., et al.
Publicado: (2016)

Application of an acoustofluidic perfusion bioreactor for cartilage tissue engineering
por: Li, Siwei, et al.
Publicado: (2014)

Osteoblasts in a Perfusion Flow Bioreactor—Tissue Engineered Constructs of TiO(2) Scaffolds and Cells for Improved Clinical Performance
por: Schröder, Maria, et al.
Publicado: (2022)

Impact of various detergent-based immersion and perfusion decellularization strategies on the novel caprine pancreas derived extracellular matrix scaffold
por: Singh, Garima, et al.
Publicado: (2023)

The Impact of Mechanically-Imposed Shear on Clogging, Fouling and Energy Demand for an Immersed Membrane Bioreactor
por: Judd, Simon, et al.
Publicado: (2018)

On the finiteness of the number of boundary slopes of immersed surfaces in 3-manifolds
por: Hass, J, et al.
Publicado: (2000)

Hybrid finite difference/finite element immersed boundary method
por: E. Griffith, Boyce, et al.
Publicado: (2017)

Immersed boundary-conformal isogeometric method for linear elliptic problems
por: Wei, Xiaodong, et al.
Publicado: (2021)

Quantifying Human Avoidance Behavior in Immersive Virtual Reality
por: Binder, Florian P., et al.
Publicado: (2020)

A Semiquantitative Framework for Gene Regulatory Networks: Increasing the Time and Quantitative Resolution of Boolean Networks
por: Kerkhofs, Johan, et al.
Publicado: (2015)

A Perfusion Bioreactor for Longitudinal Monitoring of Bioengineered Liver Constructs
por: Sassi, Lisa, et al.
Publicado: (2021)

In Vivo Ectopic Bone Formation by Devitalized Mineralized Stem Cell Carriers Produced Under Mineralizing Culture Condition
por: Chai, Yoke Chin, et al.
Publicado: (2014)

Temporary immersion bioreactor system for propagation by somatic embryogenesis of hybrid larch (Larix × eurolepis Henry)
por: Le, Kim-Cuong, et al.
Publicado: (2021)

Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects
por: Tam, Wai Long, et al.
Publicado: (2021)

Modelling and simulation of the chondrocyte cell growth, glucose consumption and lactate production within a porous tissue scaffold inside a perfusion bioreactor()
por: Hossain, Md. Shakhawath, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_e18n98bl24dk0ts5llktdsvr53