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Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing

Intratumoral genetic heterogeneity may impact disease outcome. Gold standard for dissecting clonal heterogeneity are single-cell analyses. Here, we present an efficient workflow based on an advanced Single-Cell Printer (SCP) device for the study of gene variants in single cancer cells. To allow for...

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Detalles Bibliográficos
Autores principales:	Riba, Julian, Renz, Nathalie, Niemöller, Christoph, Bleul, Sabine, Pfeifer, Dietmar, Stosch, Juliane M., Metzeler, Klaus H., Hackanson, Björn, Lübbert, Michael, Duyster, Justus, Koltay, Peter, Zengerle, Roland, Claus, Rainer, Zimmermann, Stefan, Becker, Heiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033393/ https://www.ncbi.nlm.nih.gov/pubmed/27658049 http://dx.doi.org/10.1371/journal.pone.0163455

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