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The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28

KRAB domain Zinc finger proteins are one of the most abundant families of transcriptional regulators in higher vertebrates. The prevailing view is that KRAB domain proteins function as potent transcriptional repressors by recruiting TRIM28 and promoting heterochromatin spreading. However, the extent...

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Detalles Bibliográficos
Autores principales:	Murphy, Kristin E., Shylo, Natalia A., Alexander, Katherine A., Churchill, Angela J., Copperman, Cecilia, García-García, María J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033580/ https://www.ncbi.nlm.nih.gov/pubmed/27658112 http://dx.doi.org/10.1371/journal.pone.0163555

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