The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies

Curcumin (CUR) is the major constituent of the rhizomes of Curcuma longa and has been widely investigated for its chemotherapeutic properties. The well-known activity of CUR against Leishmania sp., Trypanosoma brucei and Plasmodium falciparum led us to investigate its activity against Trypanosoma cr...

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Detalles Bibliográficos
Autores principales: Sueth-Santiago, Vitor, Moraes, Julliane de B. B., Sobral Alves, Eliomara Sousa, Vannier-Santos, Marcos André, Freire-de-Lima, Célio G., Castro, Rosane N., Mendes-Silva, Gustavo Peron, Del Cistia, Catarina de Nigris, Magalhães, Luma Godoy, Andricopulo, Adriano Defini, Sant´Anna, Carlos Mauricio R., Decoté-Ricardo, Debora, Freire de Lima, Marco Edilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033595/
https://www.ncbi.nlm.nih.gov/pubmed/27658305
http://dx.doi.org/10.1371/journal.pone.0162926

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