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Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients

BACKGROUND AND OBJECTIVE: COPD, a systemic illness associated with the impairment of different organs, affects patient prognosis and quality of life. The aim of this study was to evaluate the association between right ventricle (RV) function, the BODE (body mass index, airflow obstruction, dyspnea,...

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Autores principales: Tannus-Silva, Daniela Graner Schuwartz, Masson-Silva, João Batista, Ribeiro, Lays Silva, Conde, Marcus Barreto, Rabahi, Marcelo Fouad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033620/
https://www.ncbi.nlm.nih.gov/pubmed/27695314
http://dx.doi.org/10.2147/COPD.S110779
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author Tannus-Silva, Daniela Graner Schuwartz
Masson-Silva, João Batista
Ribeiro, Lays Silva
Conde, Marcus Barreto
Rabahi, Marcelo Fouad
author_facet Tannus-Silva, Daniela Graner Schuwartz
Masson-Silva, João Batista
Ribeiro, Lays Silva
Conde, Marcus Barreto
Rabahi, Marcelo Fouad
author_sort Tannus-Silva, Daniela Graner Schuwartz
collection PubMed
description BACKGROUND AND OBJECTIVE: COPD, a systemic illness associated with the impairment of different organs, affects patient prognosis and quality of life. The aim of this study was to evaluate the association between right ventricle (RV) function, the BODE (body mass index, airflow obstruction, dyspnea, and exercise capacity) index (a multifunctional scale for the assessment of mortality risk), and quality of life in patients with COPD. METHODS: A cross-sectional study was carried out in 107 outpatients presenting with stable COPD who underwent clinical assessment, spirometry, arterial blood gas analyses, a 6-minute walk test, electrocardiography, and echocardiogram and who responded to the Saint George’s Respiratory Questionnaire (SGRQ). RESULTS: Among the study subjects, 53% (57/107) were males, and the mean age was 65.26±8.81 years. A positive correlation was observed between RV dysfunction measured by the myocardial performance index using tissue Doppler (MPIt) and the BODE index, even after adjustment for age and partial pressure of oxygen (r(2)=0.47; P<0.01). Patients with alterations in the MPIt had worse quality of life, and a statistically significant difference was found for different domains of the SGRQ. Patients with a normal MPIt had a mean total score of 46.2±18.6, whereas for those with MPIt alterations, the mean total score was 61.6±14.2 (P=0.005). These patients had a 1.49-fold increased risk of exhibiting SGRQ total score above the upper limit of the 95% CI (P=0.01). CONCLUSION: The findings of this study suggest that RV dysfunction as measured by the MPIt was associated with impairment in quality of life and a worse BODE index in COPD patients, irrespective of age and hypoxemia status.
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spelling pubmed-50336202016-09-30 Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients Tannus-Silva, Daniela Graner Schuwartz Masson-Silva, João Batista Ribeiro, Lays Silva Conde, Marcus Barreto Rabahi, Marcelo Fouad Int J Chron Obstruct Pulmon Dis Original Research BACKGROUND AND OBJECTIVE: COPD, a systemic illness associated with the impairment of different organs, affects patient prognosis and quality of life. The aim of this study was to evaluate the association between right ventricle (RV) function, the BODE (body mass index, airflow obstruction, dyspnea, and exercise capacity) index (a multifunctional scale for the assessment of mortality risk), and quality of life in patients with COPD. METHODS: A cross-sectional study was carried out in 107 outpatients presenting with stable COPD who underwent clinical assessment, spirometry, arterial blood gas analyses, a 6-minute walk test, electrocardiography, and echocardiogram and who responded to the Saint George’s Respiratory Questionnaire (SGRQ). RESULTS: Among the study subjects, 53% (57/107) were males, and the mean age was 65.26±8.81 years. A positive correlation was observed between RV dysfunction measured by the myocardial performance index using tissue Doppler (MPIt) and the BODE index, even after adjustment for age and partial pressure of oxygen (r(2)=0.47; P<0.01). Patients with alterations in the MPIt had worse quality of life, and a statistically significant difference was found for different domains of the SGRQ. Patients with a normal MPIt had a mean total score of 46.2±18.6, whereas for those with MPIt alterations, the mean total score was 61.6±14.2 (P=0.005). These patients had a 1.49-fold increased risk of exhibiting SGRQ total score above the upper limit of the 95% CI (P=0.01). CONCLUSION: The findings of this study suggest that RV dysfunction as measured by the MPIt was associated with impairment in quality of life and a worse BODE index in COPD patients, irrespective of age and hypoxemia status. Dove Medical Press 2016-09-16 /pmc/articles/PMC5033620/ /pubmed/27695314 http://dx.doi.org/10.2147/COPD.S110779 Text en © 2016 Tannus-Silva et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Tannus-Silva, Daniela Graner Schuwartz
Masson-Silva, João Batista
Ribeiro, Lays Silva
Conde, Marcus Barreto
Rabahi, Marcelo Fouad
Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients
title Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients
title_full Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients
title_fullStr Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients
title_full_unstemmed Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients
title_short Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients
title_sort myocardial performance index correlates with the bode index and affects quality of life in copd patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033620/
https://www.ncbi.nlm.nih.gov/pubmed/27695314
http://dx.doi.org/10.2147/COPD.S110779
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