Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo

Liver kinase B1 (LKB1) and its downstream effector AMP‐activated protein kinase (AMPK) play critical roles in polarity establishment by regulating membrane trafficking and energy metabolism. In collagen sandwich‐cultured hepatocytes, loss of LKB1 or AMPK impaired apical ABCB11 (Bsep) trafficking and...

Descripción completa

Detalles Bibliográficos
Autores principales: Porat‐Shliom, Natalie, Tietgens, Amber J., Van Itallie, Christina M., Vitale‐Cross, Lynn, Jarnik, Michal, Harding, Olivia J., Anderson, James M., Gutkind, J. Silvio, Weigert, Roberto, Arias, Irwin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Liver Biology/Pathobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033699/
https://www.ncbi.nlm.nih.gov/pubmed/27396550
http://dx.doi.org/10.1002/hep.28724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033699/
https://www.ncbi.nlm.nih.gov/pubmed/27396550
http://dx.doi.org/10.1002/hep.28724

Ejemplares similares