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Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis

Necroptosis and pyroptosis are two forms of programmed cell death with a common feature of plasma membrane rupture. Here we studied the morphology and mechanism of pyroptosis in comparison with necroptosis. Different from necroptosis, pyroptosis undergoes membrane blebbing and produces apoptotic bod...

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Detalles Bibliográficos
Autores principales: Chen, Xin, He, Wan-ting, Hu, Lichen, Li, Jingxian, Fang, Yuan, Wang, Xin, Xu, Xiaozheng, Wang, Zhuo, Huang, Kai, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034106/
https://www.ncbi.nlm.nih.gov/pubmed/27573174
http://dx.doi.org/10.1038/cr.2016.100