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Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
Necroptosis and pyroptosis are two forms of programmed cell death with a common feature of plasma membrane rupture. Here we studied the morphology and mechanism of pyroptosis in comparison with necroptosis. Different from necroptosis, pyroptosis undergoes membrane blebbing and produces apoptotic bod...
Autores principales: | Chen, Xin, He, Wan-ting, Hu, Lichen, Li, Jingxian, Fang, Yuan, Wang, Xin, Xu, Xiaozheng, Wang, Zhuo, Huang, Kai, Han, Jiahuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034106/ https://www.ncbi.nlm.nih.gov/pubmed/27573174 http://dx.doi.org/10.1038/cr.2016.100 |
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