Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways

Toll-like receptors (TLRs) act as initiators and conductors responsible for both innate and adaptive immune responses in organ transplantation. The mammalian target of rapamycin (mTOR) is one of the most critical signaling kinases that affects broad aspects of cellular functions including metabolism...

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Detalles Bibliográficos
Autores principales: Wang, Hongmei, Zhang, Xusheng, Zheng, Xiufen, Lan, Zhu, Shi, Jun, Jiang, Jifu, Zwiep, Terry, Li, Qing, Quan, Douglas, Zhang, Zhu-Xu, Min, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034230/
https://www.ncbi.nlm.nih.gov/pubmed/27659428
http://dx.doi.org/10.1038/srep33869

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