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Toll-Like Receptor 9 Activation Rescues Impaired Antibody Response in Needle-free Intradermal DNA Vaccination

The delivery of plasmid DNA to the skin can target distinct subsets of dermal dendritic cells to confer a superior immune response. The needle-free immunization technology offers a reliable, safe and efficient means to administer intradermal (ID) injections. We report here that the ID injection of D...

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Detalles Bibliográficos
Autores principales: Arunachalam, Prabhu S., Mishra, Ria, Badarinath, Krithika, Selvam, Deepak, Payeli, Sravan K., Stout, Richard R., Ranga, Udaykumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034244/
https://www.ncbi.nlm.nih.gov/pubmed/27658623
http://dx.doi.org/10.1038/srep33564