The UPR inducer DPP23 inhibits the metastatic potential of MDA-MB-231 human breast cancer cells by targeting the Akt–IKK–NF-κB–MMP-9 axis

(E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one (DPP23) is a synthetic polyphenol derivative that selectively induces apoptosis in cancer cells through the unfolded protein response pathway. In the present study, we evaluated the effect of DPP23 on tumour invasion and metastasis. Here...

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Detalles Bibliográficos
Autores principales: Shin, Soon Young, Kim, Chang Gun, Jung, You Jung, Lim, Yoongho, Lee, Young Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034246/
https://www.ncbi.nlm.nih.gov/pubmed/27658723
http://dx.doi.org/10.1038/srep34134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034246/
https://www.ncbi.nlm.nih.gov/pubmed/27658723
http://dx.doi.org/10.1038/srep34134

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