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Sweeter and stronger: enhancing sweetness and stability of the single chain monellin MNEI through molecular design

Sweet proteins are a family of proteins with no structure or sequence homology, able to elicit a sweet sensation in humans through their interaction with the dimeric T1R2-T1R3 sweet receptor. In particular, monellin and its single chain derivative (MNEI) are among the sweetest proteins known to men....

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Detalles Bibliográficos
Autores principales: Leone, Serena, Pica, Andrea, Merlino, Antonello, Sannino, Filomena, Temussi, Piero Andrea, Picone, Delia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034325/
https://www.ncbi.nlm.nih.gov/pubmed/27658853
http://dx.doi.org/10.1038/srep34045