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Sweeter and stronger: enhancing sweetness and stability of the single chain monellin MNEI through molecular design
Sweet proteins are a family of proteins with no structure or sequence homology, able to elicit a sweet sensation in humans through their interaction with the dimeric T1R2-T1R3 sweet receptor. In particular, monellin and its single chain derivative (MNEI) are among the sweetest proteins known to men....
Autores principales: | Leone, Serena, Pica, Andrea, Merlino, Antonello, Sannino, Filomena, Temussi, Piero Andrea, Picone, Delia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034325/ https://www.ncbi.nlm.nih.gov/pubmed/27658853 http://dx.doi.org/10.1038/srep34045 |
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