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Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children

BACKGROUND: Outcomes of cardiopulmonary resuscitation (CPR) in children with congenital heart disease have improved and many children have survived after an in-hospital cardiac arrest. AIM: The purpose of this study is to determine predictors of poor outcome after CPR in critical children undergoing...

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Autores principales: Nasser, Bana Agha, Idris, Julinar, Mesned, Abdu Rahman, Mohamad, Tageldein, Kabbani, Mohamed S., Alakfash, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034358/
https://www.ncbi.nlm.nih.gov/pubmed/27688672
http://dx.doi.org/10.1016/j.jsha.2015.12.002
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author Nasser, Bana Agha
Idris, Julinar
Mesned, Abdu Rahman
Mohamad, Tageldein
Kabbani, Mohamed S.
Alakfash, Ali
author_facet Nasser, Bana Agha
Idris, Julinar
Mesned, Abdu Rahman
Mohamad, Tageldein
Kabbani, Mohamed S.
Alakfash, Ali
author_sort Nasser, Bana Agha
collection PubMed
description BACKGROUND: Outcomes of cardiopulmonary resuscitation (CPR) in children with congenital heart disease have improved and many children have survived after an in-hospital cardiac arrest. AIM: The purpose of this study is to determine predictors of poor outcome after CPR in critical children undergoing cardiac surgery. METHODS: We conducted a retrospective chart review and data analysis of all CPR records and charts of all postoperative cardiac children who had a cardiac arrest and required resuscitation from 2011 until 2015. Demographic, pre-operative, and postoperative data were reviewed and analyzed. RESULTS: During the study period, 18 postoperative pediatric cardiac patients had CPR. Nine of them had return of spontaneous circulation and survived (50%). On average CPR was required on the 3(rd) postoperative day. Univariate analysis demonstrated that poor outcome was associated with higher lactic acid measured 4–6 hours prior to arrest (p = 0.045; p = 0.02) coupled with higher heart rate (p = 0.031), lower O(2) saturation (p = 0.01), and lower core body temperature (p = 0.019) recorded 6 hours before arrest. Nonsurvival required longer resuscitation duration and more epinephrine doses (p < 0.05). CONCLUSION: Higher heart rate, lower core body temperature, lower O(2) saturation, and higher lactic acid measured 6 hours before arrest are possible predictors of poorer outcome and mortality following CPR in postoperative cardiac children.
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spelling pubmed-50343582016-09-29 Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children Nasser, Bana Agha Idris, Julinar Mesned, Abdu Rahman Mohamad, Tageldein Kabbani, Mohamed S. Alakfash, Ali J Saudi Heart Assoc Full Length Article BACKGROUND: Outcomes of cardiopulmonary resuscitation (CPR) in children with congenital heart disease have improved and many children have survived after an in-hospital cardiac arrest. AIM: The purpose of this study is to determine predictors of poor outcome after CPR in critical children undergoing cardiac surgery. METHODS: We conducted a retrospective chart review and data analysis of all CPR records and charts of all postoperative cardiac children who had a cardiac arrest and required resuscitation from 2011 until 2015. Demographic, pre-operative, and postoperative data were reviewed and analyzed. RESULTS: During the study period, 18 postoperative pediatric cardiac patients had CPR. Nine of them had return of spontaneous circulation and survived (50%). On average CPR was required on the 3(rd) postoperative day. Univariate analysis demonstrated that poor outcome was associated with higher lactic acid measured 4–6 hours prior to arrest (p = 0.045; p = 0.02) coupled with higher heart rate (p = 0.031), lower O(2) saturation (p = 0.01), and lower core body temperature (p = 0.019) recorded 6 hours before arrest. Nonsurvival required longer resuscitation duration and more epinephrine doses (p < 0.05). CONCLUSION: Higher heart rate, lower core body temperature, lower O(2) saturation, and higher lactic acid measured 6 hours before arrest are possible predictors of poorer outcome and mortality following CPR in postoperative cardiac children. Elsevier 2016-10 2015-12-19 /pmc/articles/PMC5034358/ /pubmed/27688672 http://dx.doi.org/10.1016/j.jsha.2015.12.002 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Full Length Article
Nasser, Bana Agha
Idris, Julinar
Mesned, Abdu Rahman
Mohamad, Tageldein
Kabbani, Mohamed S.
Alakfash, Ali
Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children
title Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children
title_full Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children
title_fullStr Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children
title_full_unstemmed Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children
title_short Predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children
title_sort predictors of cardio pulmonary resuscitation outcome in postoperative cardiac children
topic Full Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034358/
https://www.ncbi.nlm.nih.gov/pubmed/27688672
http://dx.doi.org/10.1016/j.jsha.2015.12.002
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