Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells

BACKGROUND: Hsp90 proteins are important therapeutic targets for many anti-cancer drugs in clinical trials. Geldanamycin (GA) was identified as the first natural inhibitor of Hsp90, increasing evidence suggests that GA was not a good choice for clinical trials. In this study, we investigated two new...

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Detalles Bibliográficos
Autores principales: Zhang, Zhirui, Li, Hong-Mei, Zhou, Can, Li, Qixiang, Ma, Linyan, Zhang, Zixuan, Sun, Yiming, Wang, Lirong, Zhang, Xudong, Zhu, Bing, Hong, Young-Soo, Wu, Cheng-Zhu, Liu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034425/
https://www.ncbi.nlm.nih.gov/pubmed/27658586
http://dx.doi.org/10.1186/s13046-016-0428-6

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