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Hypoxia promotes chemoresistance in acute lymphoblastic leukemia cell lines by modulating death signaling pathways

BACKGROUND: Several studies show that bone marrow (BM) microenvironment and hypoxia condition can promote the survival of leukemic cells and induce resistance to anti-leukemic drugs. However, the molecular mechanism for chemoresistance by hypoxia is not fully understood. METHODS: In the present stud...

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Detalles Bibliográficos
Autores principales:	Petit, C., Gouel, F., Dubus, I., Heuclin, C., Roget, K., Vannier, J. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034444/ https://www.ncbi.nlm.nih.gov/pubmed/27658583 http://dx.doi.org/10.1186/s12885-016-2776-1

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