Cargando…

Therapeutic drug monitoring of mexiletine at a large academic medical center

INTRODUCTION: The therapeutic trough range for mexiletine (0.8–2 mcg/mL) was largely established in the setting of arrhythmia prophylaxis following myocardial infarction. OBJECTIVE: Describe the usage patterns of serum mexiletine concentrations and the impact of these concentrations on mexiletine do...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nei, Scott D, Danelich, Ilya M, Lose, Jennifer M, Leung, Lydia Yuk Ting, Asirvatham, Samuel J, McLeod, Christopher J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034464/ https://www.ncbi.nlm.nih.gov/pubmed/27708780 http://dx.doi.org/10.1177/2050312116670659

Ejemplares similares

A patient with mexiletine-related psychosis
por: Shailesh, Fnu, et al.
Publicado: (2011)

Experience with oral mexiletine in primary erythromelalgia in children
por: Iqbal, Javeed, et al.
Publicado: (2009)

Molecular Modeling of Cardiac Sodium Channel with Mexiletine
por: Zhorov, Boris S.
Publicado: (2022)

Synergistic Effect of Dofetilide and Mexiletine on Prevention of Atrial Fibrillation
por: Liu, Guizhi, et al.
Publicado: (2017)

Long-Term Safety and Usefulness of Mexiletine in a Large Cohort of Patients Affected by Non-dystrophic Myotonias
por: Modoni, Anna, et al.
Publicado: (2020)

Embryology of the Conduction System for the Electrophysiologist
por: Mirzoyev, Sultan, et al.
Publicado: (2010)

Characterisation of mexiletine’s translational therapeutic index for suppression of ischaemia-induced ventricular fibrillation in the rat isolated heart
por: Hesketh, Louise M., et al.
Publicado: (2020)

Management of ventricular tachycardia--role of mexiletine : proceedings of a symposium held in Copenhagen, Denmark, 25th-27th May, 1978 /
Publicado: (1978)

A Case of Mexiletine-induced Hypersensitivity Syndrome Presenting as Eosinophilic Pneumonia
por: Lee, Sang-Pyo, et al.
Publicado: (2010)

Case report: Mexiletine suppresses ventricular arrhythmias in Andersen-Tawil syndrome
por: Yang, Jing, et al.
Publicado: (2022)

Mexiletine in spinal and bulbar muscular atrophy: a randomized controlled trial
por: Yamada, Shinichiro, et al.
Publicado: (2022)

Ventricular tachycardia secondary to abandoned epicardial pacemaker lead
por: Witt, Chance M., et al.
Publicado: (2015)

Effectiveness and safety of mexiletine in patients at risk for (recurrent) ventricular arrhythmias: a systematic review
por: van der Ree, Martijn H, et al.
Publicado: (2022)

Mexiletine Differentially Restores the Trafficking Defects Caused by Two Brugada Syndrome Mutations
por: Moreau, Adrien, et al.
Publicado: (2012)

Mexiletine Treatment for Neonatal LQT3 Syndrome: Case Report and Literature Review
por: Bagkaki, Alena, et al.
Publicado: (2021)

Mexiletine and False Positive Urine Drug Screen for Amphetamine: A Case Review
por: Sohal, Sumit, et al.
Publicado: (2021)

Mexiletine-like cellular electrophysiological effects of GS967 in canine ventricular myocardium
por: Hézső, Tamás, et al.
Publicado: (2021)

Designer Gelators for the Crystallization of a Salt Active Pharmaceutical Ingredient—Mexiletine Hydrochloride
por: Andrews, Jessica L., et al.
Publicado: (2022)

Dual chamber pacing mode in an atrial antitachycardia pacing device without a ventricular lead – A necessary evil
por: Noheria, Amit, et al.
Publicado: (2015)

Stage A: Can Heart Failure Be Prevented?
por: Danelich, Ilya M, et al.
Publicado: (2015)

Interactions of Mexiletine with Novel Antiepileptic Drugs in the Maximal Electroshock Test in Mice: An Isobolographic Analysis
por: Wróblewska, Dorota, et al.
Publicado: (2018)

Characterization of a novel LQT3 variant with a selective efficacy of mexiletine treatment
por: Kim, Hyun-Ji, et al.
Publicado: (2019)

Successful Ablation of a Left-Sided Accessory Pathway in a Patient with Coronary Sinus Atresia and Arteriovenous Fistula: Clinical and Developmental Insights
por: Patel, Sandeep M, et al.
Publicado: (2011)

A comparative study of serotonin and norepinephrine as adjuncts to improve cutaneous antinociception of mexiletine in response to skin pinpricks in rats
por: Han, Mingming, et al.
Publicado: (2021)

Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine
por: Gualdani, Roberta, et al.
Publicado: (2015)

Mexiletine infusion challenge test for neonatal long QT syndrome with 2:1 atrioventricular block
por: Okuwaki, Hajime, et al.
Publicado: (2019)

Mexiletine shortens the QT interval in a pedigree of KCNH2 related long QT syndrome
por: Fujisawa, Taishi, et al.
Publicado: (2020)

1241. Outcomes of a Novel Antimicrobial Handshake Stewardship Service in the Immunocompromised Population at an Academic Medical Center
por: Gomez, Keven, et al.
Publicado: (2023)

Gene-Specific Therapy With Mexiletine Reduces Arrhythmic Events in Patients With Long QT Syndrome Type 3
por: Mazzanti, Andrea, et al.
Publicado: (2016)

The Effect of Sodium Channel Blocker, Mexiletine, on Body Weight in Type 2 Diabetes Patients with Visceral Obesity
por: Ueno, Naohiko
Publicado: (2019)

Beneficial effects of chronic mexiletine treatment in a human model of SCN5A overlap syndrome
por: Nasilli, Giovanna, et al.
Publicado: (2023)

A comparative study on the effect of dopamine vs phenylephrine in improving the cutaneous analgesic effect of mexiletine in rats
por: Zheng, Kesong, et al.
Publicado: (2023)

1101. Implementing a Beta-Lactam Therapeutic Drug Monitoring Program: Experience from a Large Academic Medical Center
por: Veena, Venugopalan, et al.
Publicado: (2021)

Combined N-of-1 trials to investigate mexiletine in non-dystrophic myotonia using a Bayesian approach; study rationale and protocol
por: Stunnenberg, Bas C, et al.
Publicado: (2015)

Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study
por: Ruijs, Titia Q., et al.
Publicado: (2022)

Molecular Insights into the Local Anesthetic Receptor within Voltage-Gated Sodium Channels Using Hydroxylated Analogs of Mexiletine
por: Desaphy, Jean-François, et al.
Publicado: (2012)

Anti-Bronchospasmodic Effect of JME-173, a Novel Mexiletine Analog Endowed With Highly Attenuated Anesthetic Activity
por: Carvalho, Katharinne Ingrid Moraes, et al.
Publicado: (2020)

Human‐induced pluripotent stem cell‐derived cardiomyocytes: Cardiovascular properties and metabolism and pharmacokinetics of deuterated mexiletine analogs
por: Gomez‐Galeno, Jorge, et al.
Publicado: (2021)

Chiral Discrimination of Mexiletine Enantiomers by Capillary Electrophoresis Using Cyclodextrins as Chiral Selectors and Experimental Design Method Optimization
por: Cârcu-Dobrin, Melania, et al.
Publicado: (2022)

Effects of Mexiletine on a Race-specific Mutation in Na(v)1.5 Associated With Long QT Syndrome
por: Wu, Xin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1515dhop6dhtra09gro3l740rj