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Novel regional age-associated DNA methylation changes within human common disease-associated loci

BACKGROUND: Advancing age progressively impacts on risk and severity of chronic disease. It also modifies the epigenome, with changes in DNA methylation, due to both random drift and variation within specific functional loci. RESULTS: In a discovery set of 2238 peripheral-blood genome-wide DNA methy...

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Detalles Bibliográficos
Autores principales:	Bell, Christopher G., Xia, Yudong, Yuan, Wei, Gao, Fei, Ward, Kirsten, Roos, Leonie, Mangino, Massimo, Hysi, Pirro G., Bell, Jordana, Wang, Jun, Spector, Timothy D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034469/ https://www.ncbi.nlm.nih.gov/pubmed/27663977 http://dx.doi.org/10.1186/s13059-016-1051-8

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