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Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles

BACKGROUND: Nuclear Factor-Kappa B (NF-kB) is a family of transcription factors that are important in embryonic development, inflammation, epithelial-to-mesenchymal transition and cancer. The 65 kDa RelA subunit is the major transcriptional activator of the NF-kB pathways. Whole-body deficiency of R...

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Detalles Bibliográficos
Autores principales:	Ijaz, Talha, Wakamiya, Maki, Sun, Hong, Recinos, Adrian, Tilton, Ronald G., Brasier, Allan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034478/ https://www.ncbi.nlm.nih.gov/pubmed/27662828 http://dx.doi.org/10.1186/s12861-016-0135-8

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