Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas

BACKGROUND: Reports of exocrine-to-endocrine reprogramming through expression or stabilization of the transcription factor neurogenin 3 (NGN3) have generated renewed interest in harnessing pancreatic plasticity for therapeutic applications. NGN3 is expressed by a population of endocrine progenitor c...

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Detalles Bibliográficos
Autores principales: Shamblott, Michael J., O’Driscoll, Marci L., Gomez, Danielle L., McGuire, Dustin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034529/
https://www.ncbi.nlm.nih.gov/pubmed/27659207
http://dx.doi.org/10.1186/s12964-016-0146-x

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