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Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis

The activity of cysteine cathepsin B increased markedly in lung homogenates and in bronchoalveolar lavage fluids (BALF) of the mouse model of bleomycin-induced lung fibrosis after 14 days of challenge. In contrast the level of the cysteine cathepsin inhibitor cystatin C was unaffected in BALF of wil...

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Detalles Bibliográficos
Autores principales: Kasabova, Mariana, Villeret, Bérengère, Gombault, Aurélie, Lecaille, Fabien, Reinheckel, Thomas, Marchand-Adam, Sylvain, Couillin, Isabelle, Lalmanach, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034538/
https://www.ncbi.nlm.nih.gov/pubmed/27658724
http://dx.doi.org/10.1186/s12931-016-0432-6