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Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis
The activity of cysteine cathepsin B increased markedly in lung homogenates and in bronchoalveolar lavage fluids (BALF) of the mouse model of bleomycin-induced lung fibrosis after 14 days of challenge. In contrast the level of the cysteine cathepsin inhibitor cystatin C was unaffected in BALF of wil...
Autores principales: | Kasabova, Mariana, Villeret, Bérengère, Gombault, Aurélie, Lecaille, Fabien, Reinheckel, Thomas, Marchand-Adam, Sylvain, Couillin, Isabelle, Lalmanach, Gilles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034538/ https://www.ncbi.nlm.nih.gov/pubmed/27658724 http://dx.doi.org/10.1186/s12931-016-0432-6 |
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