Cargando…

The inflammasome pathway in stable COPD and acute exacerbations

Chronic obstructive pulmonary disease (COPD) is characterised by pulmonary and systemic inflammation that bursts during exacerbations of the disease (ECOPD). The NLRP3 inflammasome is a key regulatory molecule of the inflammatory response. Its role in COPD is unclear. We investigated the NLRP3 infla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Faner, Rosa, Sobradillo, Patricia, Noguera, Aina, Gomez, Cristina, Cruz, Tamara, López-Giraldo, Alejandra, Ballester, Eugeni, Soler, Nestor, Arostegui, Juan I., Pelegrín, Pablo, Rodriguez-Roisin, Roberto, Yagüe, Jordi, Cosio, Borja G., Juan, Manel, Agustí, Alvar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034597/ https://www.ncbi.nlm.nih.gov/pubmed/27730204 http://dx.doi.org/10.1183/23120541.00002-2016

Ejemplares similares

An investigation of the resolution of inflammation (catabasis) in COPD
por: Noguera, Aina, et al.
Publicado: (2012)

The EASI model: A first integrative computational approximation to the natural history of COPD
por: Agustí, Alvar, et al.
Publicado: (2017)

Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD)
por: Cruz, Tamara, et al.
Publicado: (2019)

Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD
por: Casas-Recasens, Sandra, et al.
Publicado: (2021)

Network medicine analysis of COPD multimorbidities
por: Grosdidier, Solène, et al.
Publicado: (2014)

Using the Electronic Nose to Identify Airway Infection during COPD Exacerbations
por: Shafiek, Hanaa, et al.
Publicado: (2015)

Characterization, localization and comparison of c-Kit+ lung cells in never smokers and smokers with and without COPD
por: López-Giraldo, Alejandra, et al.
Publicado: (2018)

When Harry Met Sally, or When Machine Learning Met Chronic Obstructive Pulmonary Disease
por: Agusti, Alvar, et al.
Publicado: (2020)

Relationship between the respiratory microbiome and the severity of airflow limitation, history of exacerbations and circulating eosinophils in COPD patients
por: Millares, Laura, et al.
Publicado: (2019)

Molecular Interactions of SARS-CoV-2 in Lung Tissue of Patients with Chronic Obstructive Pulmonary Disease
por: Agusti, Alvar, et al.
Publicado: (2021)

Bone marrow characterization in COPD: a multi-level network analysis
por: Toledo-Pons, Nuria, et al.
Publicado: (2018)

Haemophilus influenzae induces steroid-resistant inflammatory responses in COPD
por: Cosío, Borja G., et al.
Publicado: (2015)

Early treatment with inhaled budesonide to prevent clinical deterioration in patients with COVID-19
por: Agusti, Alvar, et al.
Publicado: (2021)

From systems biology to P4 medicine: applications in respiratory medicine
por: Noell, Guillaume, et al.
Publicado: (2018)

Liver epigenome changes in patients with hepatopulmonary syndrome: A pilot study
por: Mendoza, Nuria, et al.
Publicado: (2021)

Circulating eosinophil levels do not predict severe exacerbations in COPD: a retrospective study
por: Adir, Yochai, et al.
Publicado: (2018)

Reply to Guo et al.
por: Wang, Gang, et al.
Publicado: (2023)

Real-life burden of hospitalisations due to COPD exacerbations in Spain
por: Izquierdo, José Luis, et al.
Publicado: (2022)

SARS-CoV-2 T-cell response in COVID-19 convalescent patients with and without lung sequelae
por: Cruz, Tamara, et al.
Publicado: (2022)

Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis
por: Faner, Rosa, et al.
Publicado: (2019)

Systemic Inflammatory Response to Smoking in Chronic Obstructive Pulmonary Disease: Evidence of a Gender Effect
por: Faner, Rosa, et al.
Publicado: (2014)

Pulmonary and systemic hepatocyte and keratinocyte growth factors in patients with chronic obstructive pulmonary disease
por: Sauleda, Jaume, et al.
Publicado: (2008)

Do chronic respiratory diseases or their treatment affect the risk of SARS-CoV-2 infection?
por: Halpin, David M G, et al.
Publicado: (2020)

Cellular Senescence in Lung Fibrosis
por: Hernandez-Gonzalez, Fernanda, et al.
Publicado: (2021)

Phenotypic characterisation of early COPD: a prospective case–control study
por: Cosío, Borja G., et al.
Publicado: (2020)

Lack of Clinical Control in COPD Patients Depending on the Target and the Therapeutic Option
por: Soler-Cataluña, Juan José, et al.
Publicado: (2023)

Clinical Control Criteria to Determine Disease Control in Patients with Severe COPD: The CLAVE Study
por: Soler-Cataluña, Juan José, et al.
Publicado: (2021)

Natural history of COPD: gaps and opportunities
por: Agustí, Alvar, et al.
Publicado: (2017)

Systemic inflammation after inspiratory loading in chronic obstructive pulmonary disease
por: Fuster, Antonia, et al.
Publicado: (2008)

Effect of Aclidinium Bromide on Exacerbations in Patients with Moderate-to-Severe COPD: A Pooled Analysis of Five Phase III, Randomized, Placebo-Controlled Studies
por: Wedzicha, Jadwiga A., et al.
Publicado: (2016)

COPD: time to improve its taxonomy?
por: Celli, Bartolomé R., et al.
Publicado: (2018)

COPD Exacerbation Syndrome: The Spanish Perspective on an Old Dilemma
por: Soler-Cataluña, Juan Jose, et al.
Publicado: (2022)

Inhaled corticosteroids for the treatment of COVID-19
por: Bafadhel, Mona, et al.
Publicado: (2022)

NLRP3 inflammasome activity is upregulated in an in-vitro model of COPD exacerbation
por: Nachmias, Noy, et al.
Publicado: (2019)

Effects of simvastatin in chronic obstructive pulmonary disease: Results of a pilot, randomized, placebo-controlled clinical trial
por: Balaguer, Catalina, et al.
Publicado: (2016)

Lytic cell death induced by melittin bypasses pyroptosis but induces NLRP3 inflammasome activation and IL-1β release
por: Martín-Sánchez, Fátima, et al.
Publicado: (2017)

ASC nanobodies to counteract the consequences of inflammasome activation
por: Adriouch, Sahil, et al.
Publicado: (2022)

Clinical Audit of COPD Patients Requiring Hospital Admissions in Spain: AUDIPOC Study
por: Pozo-Rodríguez, Francisco, et al.
Publicado: (2012)

The Role of IL-33/ST2 in COPD and Its Future as an Antibody Therapy
por: Riera-Martínez, Lluc, et al.
Publicado: (2023)

Long-Term Responders After Autologous Stem Cell Transplantation in Multiple Myeloma
por: Oliver-Caldes, Aina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dtjnlfsup6u51nh6u9fpbrmdk2