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Roux-en-Y gastric bypass surgery is effective in fibroblast growth factor-21 deficient mice

OBJECTIVE: The mechanisms by which bariatric surgeries so effectively and lastingly reduce body weight and normalize metabolic dysfunction are not well understood. Fibroblast growth fator-21 (FGF21) is a key regulator of metabolism and is currently considered for treatment of obesity. Although eleva...

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Detalles Bibliográficos
Autores principales: Morrison, Christopher D., Hao, Zheng, Mumphrey, Michael B., Townsend, R. Leigh, Münzberg, Heike, Ye, Jianping, Berthoud, Hans-Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034607/
https://www.ncbi.nlm.nih.gov/pubmed/27689013
http://dx.doi.org/10.1016/j.molmet.2016.08.005