Cargando…
Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty
OBJECTIVE: Puberty is a key developmental phenomenon highly sensitive to metabolic modulation. Worrying trends of changes in the timing of puberty have been reported in humans. These might be linked to the escalating prevalence of childhood obesity and could have deleterious impacts on later (cardio...
Autores principales: | Manfredi-Lozano, Maria, Roa, Juan, Ruiz-Pino, Francisco, Piet, Richard, Garcia-Galiano, David, Pineda, Rafael, Zamora, Aurora, Leon, Silvia, Sanchez-Garrido, Miguel A., Romero-Ruiz, Antonio, Dieguez, Carlos, Vazquez, Maria Jesus, Herbison, Allan E., Pinilla, Leonor, Tena-Sempere, Manuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034608/ https://www.ncbi.nlm.nih.gov/pubmed/27688998 http://dx.doi.org/10.1016/j.molmet.2016.08.003 |
Ejemplares similares
-
Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity
por: León, Silvia, et al.
Publicado: (2016) -
Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty
por: Sangiao-Alvarellos, S., et al.
Publicado: (2015) -
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3
por: Heras, Violeta, et al.
Publicado: (2019) -
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice
por: Roa, Juan, et al.
Publicado: (2022) -
A synthetic kisspeptin analog that triggers ovulation and advances puberty
por: Decourt, C., et al.
Publicado: (2016)