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Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis

OBJECTIVE: DNA methylation may be a stable epigenetic contributor to defining fat cell lineage. METHODS: We performed reduced representation bisulfite sequencing (RRBS) and RNA-seq to depict a genome-wide integrative view of the DNA methylome and transcriptome during brown and white adipogenesis. RE...

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Detalles Bibliográficos
Autores principales: Lim, Yen Ching, Chia, Sook Yoong, Jin, Shengnan, Han, Weiping, Ding, Chunming, Sun, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034609/
https://www.ncbi.nlm.nih.gov/pubmed/27689016
http://dx.doi.org/10.1016/j.molmet.2016.08.006