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A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens

BACKGROUND: The polymorphic nature of many malaria vaccine candidates presents major challenges to achieving highly efficacious vaccines. Presently, there is very little knowledge on the prevalence and patterns of functional immune responses to polymorphic vaccine candidates in populations to guide...

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Detalles Bibliográficos
Autores principales: Drew, Damien R., Wilson, Danny W., Elliott, Salenna R., Cross, Nadia, Terheggen, Ulrich, Hodder, Anthony N., Siba, Peter M., Chelimo, Kiprotich, Dent, Arlene E., Kazura, James W., Mueller, Ivo, Beeson, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034621/
https://www.ncbi.nlm.nih.gov/pubmed/27658419
http://dx.doi.org/10.1186/s12916-016-0691-6