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A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens
BACKGROUND: The polymorphic nature of many malaria vaccine candidates presents major challenges to achieving highly efficacious vaccines. Presently, there is very little knowledge on the prevalence and patterns of functional immune responses to polymorphic vaccine candidates in populations to guide...
Autores principales: | Drew, Damien R., Wilson, Danny W., Elliott, Salenna R., Cross, Nadia, Terheggen, Ulrich, Hodder, Anthony N., Siba, Peter M., Chelimo, Kiprotich, Dent, Arlene E., Kazura, James W., Mueller, Ivo, Beeson, James G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034621/ https://www.ncbi.nlm.nih.gov/pubmed/27658419 http://dx.doi.org/10.1186/s12916-016-0691-6 |
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